Everton v Preston North End team news: Goodison Park start for teenager Ethan Walker
The Preston-born winger, 18, came through the PNE academy and has made two first-team appearances as a substitute previously.
It was a completely changed side to the one which started Friday's 2-2 draw with Sheffield United.
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Hide AdThose who started at Bramall Lane were on the bench for the visit to the blue half of Merseyside.
Although Everton were missing a number of players because of international duty, they were still able to include the Premier League quality of Richarlison,Dominic Calvert-Lewin, Theo Walcott and Gylfi Sigurdsson.
Everton: Tyrer, Kenny, Holgate, Gibson, Nkounkou, Sigurdsson, Gordon, Bernard, Walcott, Richarlison, Calvert-Lewin. Subs: Hansen, Baningime, Bolasie, Adeniran, John, Simms
PNE: Ripley, Fisher, Huntington, Storey, Earl, Bayliss, Gallagher, Potts, Harrop, Walker, Stockley. Subs: Pearson, Bauer, Davies, Johnson, Rafferty, Hughes, Ledson, Barkhuizen, Baxter, O'Reilly, Bodin, Hudson.
Referee: Robert Jones (Merseyside)