The former Blackburn Rovers midfielder has revealed that Andrew Teague, Jamie Vermiglio, John Cunliffe and Steve Flitcroft are struggling to be fit for the game.
Despite the growing injury list, Flitcroft is confident that the Magpies can pick up a result at Victory Park.
He said: “We drew with them 1-1 at their place so we know that we can compete with them.
“It is just about getting as many points as we can until the end of the season with the players we have got.
“Skelm are a tough side to beat and they are still pushing for the league title with Chester.
“The lads will be up for the game and we seem to perform better against the top sides.”
The Chorley boss was disappointed after Harrogate Railway Athletic completed the double over his side.
However, he refused to rule his side out of the promotion race.
“I am 100 per cent confident that we will be in the play-offs,” he said.
“We are not on a bad run because in March we won six matches and only lost two.
“We had enough chances to win the game and Steve Foster went through on goal three times and scored once.
“When you look at the games against Harrogate and Garforth they play with two big lads up front.
“They don’t really play football on the ground and we are not up for that.
“We have missed Wayne Maden who would have been able to look after that and need to address it for next season.”
Speaking after watching fellow play-off contenders Curzon Ashton slip up 2-1 against Warrington Town, Flitcroft expects there to be more twists and turns in the final 10 games of the season.
He said: “I thought that Curzon would have won that game and showed us why they were fifth in the league.
“Warrington had to win just so that they kept in touch with Curzon for the play-offs.”